Wuhan Hengwo Scien-Tech Co,ltd

Assay: 99% min.

CAS: 330784-47-9

Molecular Formula:C23H26ClN7O3

Molecular Weight:483.9506

Character: White to Off-White Cyrstalline Solid.

Usage: Used for the treatment of erectile dysfunction. A phosphodiesterase 5 inhibitor.

Categories: Active Pharmaceutical Ingredients; Cnbio; Erectile Dysfunction; Inhibitors; Intermediates &

Fine Chemicals; Pharmaceuticals; API's.

Applications:

Avanafil occurs as white crystalline powder, molecular formula C23H26ClN7O3 and molecular weight of 483.95 and is slightly soluble in ethanol, practically insoluble in water, and soluble in 0.1 mol/L hydrochloric acid. STENDRA, for oral administration, is supplied as oval, pale yellow tablets containing 50 mg, 100 mg, or 200 mg avanafil debossed with dosage strengths. In addition to the active ingredient, avanafil, each tablet contains the following inactive ingredients: mannitol, fumaric acid, hydroxypropylcellulose, low substituted hydroxypropylcellulose, calcium carbonate, magnesium stearate, and ferric oxide yellow.

Avanafil comes as a tablet to take by mouth. It is usually taken with or without food as needed, about 30 minutes before sexual activity. Do not take avanafil more often than once in 24 hours. Follow the directions on your prescription label carefully, and ask your doctor or pharmacist to explain any part you do not understand. Take avanafil exactly as directed. Do not take more or less of it or take it more often than prescribed by your doctor.

Your doctor will probably start you on an average dose of avanafil and may increase or decrease your dose depending on how you respond to the medication. Tell your doctor if avanafil is not working well or if you experience side effects.

How to use avanafil:

An extra patient leaflet is available with avanafil. Talk to your pharmacist if you have questions about this information.

Take avanafil by mouth with or without food.

Take avanafil before sexual activity as you were told by your doctor. If you are not sure when to take avanafil, talk with your doctor.

Do NOT take more than the recommended dose without checking with your doctor. Do NOT take avanafil more often than 1 time daily.

Eating grapefruit or drinking grapefruit juice may increase the amount of avanafil in your blood, which may increase your risk of side effects. Talk with your doctor before including grapefruit or grapefruit juice in your diet.

If you miss a dose of avanafil and you still intend to engage in sexual activity, take it as soon as you remember. Continue to take it as directed by your doctor.

Ask your health care provider any questions you may have about how to use avanafil.